http://120.24.161.253:5617/index.php?action=history&feed=atom&title=%E7%BB%93%E8%8A%82%E6%80%A7%E7%A1%AC%E5%8C%96%E7%97%87-%E5%90%8C%E4%B9%89%E8%AF%8D-TSC 2026-05-09T17:38:29Z 本wiki的该页面的版本历史 MediaWiki 1.30.0 http://120.24.161.253:5617/index.php?title=%E7%BB%93%E8%8A%82%E6%80%A7%E7%A1%AC%E5%8C%96%E7%97%87-%E5%90%8C%E4%B9%89%E8%AF%8D-TSC&diff=2027756&oldid=prev 2026-04-16T04:37:43Z

<p>导入1个版本</p> <table class="diff diff-contentalign-left" data-mw="interface"> <tr style="vertical-align: top;" lang="zh-CN"> <td colspan="1" style="background-color: white; color:black; text-align: center;">←上一版本</td> <td colspan="1" style="background-color: white; color:black; text-align: center;">2026年4月16日 (四) 04:37的版本</td> </tr><tr><td colspan="2" style="text-align: center;" lang="zh-CN"><div class="mw-diff-empty">（没有差异）</div> </td></tr></table>

KGadmin http://120.24.161.253:5617/index.php?title=%E7%BB%93%E8%8A%82%E6%80%A7%E7%A1%AC%E5%8C%96%E7%97%87-%E5%90%8C%E4%B9%89%E8%AF%8D-TSC&diff=2007130&oldid=prev 2026-04-15T13:16:57Z

<p>导入1个版本</p> <table class="diff diff-contentalign-left" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr style="vertical-align: top;" lang="zh-CN"> <td colspan="2" style="background-color: white; color:black; text-align: center;">←上一版本</td> <td colspan="2" style="background-color: white; color:black; text-align: center;">2026年4月15日 (三) 13:16的版本</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l5" >第5行：</td> <td colspan="2" class="diff-lineno">第5行：</td></tr> <tr><td class='diff-marker'>&#160;</td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'>&#160;</td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td></tr> <tr><td class='diff-marker'>&#160;</td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>==来源==</div></td><td class='diff-marker'>&#160;</td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>==来源==</div></td></tr> <tr><td class='diff-marker'>−</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>===<del class="diffchange diffchange-inline">与结节性硬化症相关的巨大双侧肾血管平滑肌脂肪瘤1例</del>===</div></td><td class='diff-marker'>+</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>===<ins class="diffchange diffchange-inline">结节性硬化症临床研究进展</ins>===</div></td></tr> <tr><td class='diff-marker'>−</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del class="diffchange diffchange-inline">故考虑该患儿为</del>[[结节性硬化症]](<del class="diffchange diffchange-inline">tuberous sclerosis，</del>[[TSC]])<del class="diffchange diffchange-inline">合并RAML，决定先开腹活检明确，活检提示肿瘤组织见大量扭曲的厚壁血管，由血管周围梭形或上皮样细胞及少量脂肪组织混杂构成，细胞核分裂少见。</del></div></td><td class='diff-marker'>+</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins class="diffchange diffchange-inline">目前研究发现</ins>[[结节性硬化症]]<ins class="diffchange diffchange-inline">基因1、2</ins>([[TSC]]<ins class="diffchange diffchange-inline">1、[[TSC]]2</ins>)<ins class="diffchange diffchange-inline">是其致病基因,该文就[[TSC]]发病机制及最新研究综述如下.</ins></div></td></tr> <tr><td class='diff-marker'>&#160;</td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'>&#160;</td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td></tr> <tr><td class='diff-marker'>−</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>===<del class="diffchange diffchange-inline">局灶性皮层发育不良发病机制研究进展</del>===</div></td><td class='diff-marker'>+</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>===<ins class="diffchange diffchange-inline">新生儿结节性硬化症</ins>===</div></td></tr> <tr><td class='diff-marker'>−</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del class="diffchange diffchange-inline">近几年FCD的发病机制已经被提出，磷脂酰肌醇3-激酶-蛋白激酶-雷帕霉素靶蛋白(PI3K-AKT-mTOR)信号通路的激活、GATOR对mTOR的作用、</del>[[结节性硬化症]]([[TSC]])<del class="diffchange diffchange-inline">基因突变、PTKs信号通路的基因突变、GABA受体假说、TRPC的激活、炎症等均可导致FCD，从而引发癫痫。</del></div></td><td class='diff-marker'>+</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>[[结节性硬化症]](<ins class="diffchange diffchange-inline">tuberous sclerosis complex,</ins>[[TSC]])<ins class="diffchange diffchange-inline">是一种常染色体显性遗传病,发病率为1/6000～1/10000.[[TSC]]患儿的临床表现具有年龄依赖性,新生儿期症状常不典型,临床上容易漏诊及误诊.</ins></div></td></tr> <tr><td class='diff-marker'>&#160;</td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'>&#160;</td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td></tr> <tr><td class='diff-marker'>−</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>===<del class="diffchange diffchange-inline">一例结节性硬化症新生儿的TSC2基因变异分析</del>===</div></td><td class='diff-marker'>+</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>===<ins class="diffchange diffchange-inline">结节性硬化症患儿的临床、视频脑电图与影像学特征</ins>===</div></td></tr> <tr><td class='diff-marker'>−</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del class="diffchange diffchange-inline">分析一例</del>[[结节性硬化症]](<del class="diffchange diffchange-inline">tuberous sclerosis complex，</del>[[TSC]])<del class="diffchange diffchange-inline">新生儿的临床特点及遗传学特征。</del></div></td><td class='diff-marker'>+</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins class="diffchange diffchange-inline">目的 分析</ins>[[结节性硬化症]]([[TSC]])<ins class="diffchange diffchange-inline">患儿的临床、视频脑电图(VEEG)和影像学特征.</ins></div></td></tr> <tr><td class='diff-marker'>&#160;</td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'>&#160;</td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td></tr> <tr><td class='diff-marker'>−</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>===<del class="diffchange diffchange-inline">雷帕霉素治疗儿童结节性硬化症合并肾血管周上皮样细胞瘤2例</del>===</div></td><td class='diff-marker'>+</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>===<ins class="diffchange diffchange-inline">结节性硬化症一家系4例报告</ins>===</div></td></tr> <tr><td class='diff-marker'>−</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>[[结节性硬化症]](<del class="diffchange diffchange-inline">tuberous sclerosis complex，</del>[[TSC]])<del class="diffchange diffchange-inline">是一种常染色体显性遗传病，影响多个器官系统，发病率为1</del>/<del class="diffchange diffchange-inline">9000~</del>1/<del class="diffchange diffchange-inline">6000，其中1/3有家族史，2/3为散发病例。</del></div></td><td class='diff-marker'>+</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>[[结节性硬化症]]([[TSC]])<ins class="diffchange diffchange-inline">是一种常染色体显性遗传病,发病率为1</ins>/<ins class="diffchange diffchange-inline">600-</ins>1/<ins class="diffchange diffchange-inline">15400,以皮脂腺瘤,癫痫,智力低下为主要临床表现.</ins></div></td></tr> <tr><td class='diff-marker'>&#160;</td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'>&#160;</td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td></tr> <tr><td class='diff-marker'>−</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>===<del class="diffchange diffchange-inline">一个结节性硬化症家系的临床表现及遗传学分析</del>===</div></td><td class='diff-marker'>+</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>===<ins class="diffchange diffchange-inline">结节性硬化的基因研究与诊断</ins>===</div></td></tr> <tr><td class='diff-marker'>−</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del class="diffchange diffchange-inline">明确1例临床诊断为</del>[[结节性硬化症]](<del class="diffchange diffchange-inline">tuberous sclerosis complex，</del>[[TSC]])<del class="diffchange diffchange-inline">患者的致病基因，为临床诊断及遗传咨询提供依据。</del></div></td><td class='diff-marker'>+</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>[[结节性硬化症]]([[TSC]])<ins class="diffchange diffchange-inline">是一种常染色体显性遗传疾病,由[[TSC]]1和[[TSC]]2两个基因异常引起,临床以智力低下、癫痫和面部血管纤维瘤三联症为主要表现,身体其他器官、组织也可受累.</ins></div></td></tr> <tr><td class='diff-marker'>&#160;</td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'>&#160;</td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td></tr> <tr><td class='diff-marker'>−</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>===<del class="diffchange diffchange-inline">结节性硬化症患者基因突变与临床表型的关系</del>===</div></td><td class='diff-marker'>+</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>===<ins class="diffchange diffchange-inline">CT和MRI在结节性硬化症中的诊断价值</ins>===</div></td></tr> <tr><td class='diff-marker'>−</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>[[结节性硬化症]](<del class="diffchange diffchange-inline">tuberoussclerosiscomplex，</del>[[TSC]])<del class="diffchange diffchange-inline">是一种常染色体显性遗传、以多器官错构瘤为特征的疾病，特别是在脑部、肾脏、心脏和皮肤。</del></div></td><td class='diff-marker'>+</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins class="diffchange diffchange-inline">目的 研究CT及MRI在</ins>[[结节性硬化症]](<ins class="diffchange diffchange-inline">Tuberous Sclerosis Complex简写</ins>[[TSC]])<ins class="diffchange diffchange-inline">中的诊断价值.</ins></div></td></tr> </table>

KGadmin http://120.24.161.253:5617/index.php?title=%E7%BB%93%E8%8A%82%E6%80%A7%E7%A1%AC%E5%8C%96%E7%97%87-%E5%90%8C%E4%B9%89%E8%AF%8D-TSC&diff=2027755&oldid=prev 2026-04-13T13:56:59Z

<p>修改1</p> <table class="diff diff-contentalign-left" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr style="vertical-align: top;" lang="zh-CN"> <td colspan="2" style="background-color: white; color:black; text-align: center;">←上一版本</td> <td colspan="2" style="background-color: white; color:black; text-align: center;">2026年4月13日 (一) 13:56的版本</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l5" >第5行：</td> <td colspan="2" class="diff-lineno">第5行：</td></tr> <tr><td class='diff-marker'>&#160;</td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'>&#160;</td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td></tr> <tr><td class='diff-marker'>&#160;</td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>==来源==</div></td><td class='diff-marker'>&#160;</td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"><div>==来源==</div></td></tr> <tr><td class='diff-marker'>−</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>===<del class="diffchange diffchange-inline">结节性硬化症临床研究进展</del>===</div></td><td class='diff-marker'>+</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>===<ins class="diffchange diffchange-inline">与结节性硬化症相关的巨大双侧肾血管平滑肌脂肪瘤1例</ins>===</div></td></tr> <tr><td class='diff-marker'>−</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del class="diffchange diffchange-inline">目前研究发现</del>[[结节性硬化症]]<del class="diffchange diffchange-inline">基因1、2</del>([[TSC]]<del class="diffchange diffchange-inline">1、[[TSC]]2</del>)<del class="diffchange diffchange-inline">是其致病基因,该文就[[TSC]]发病机制及最新研究综述如下.</del></div></td><td class='diff-marker'>+</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins class="diffchange diffchange-inline">故考虑该患儿为</ins>[[结节性硬化症]](<ins class="diffchange diffchange-inline">tuberous sclerosis，</ins>[[TSC]])<ins class="diffchange diffchange-inline">合并RAML，决定先开腹活检明确，活检提示肿瘤组织见大量扭曲的厚壁血管，由血管周围梭形或上皮样细胞及少量脂肪组织混杂构成，细胞核分裂少见。</ins></div></td></tr> <tr><td class='diff-marker'>&#160;</td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'>&#160;</td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td></tr> <tr><td class='diff-marker'>−</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>===<del class="diffchange diffchange-inline">新生儿结节性硬化症</del>===</div></td><td class='diff-marker'>+</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>===<ins class="diffchange diffchange-inline">局灶性皮层发育不良发病机制研究进展</ins>===</div></td></tr> <tr><td class='diff-marker'>−</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>[[结节性硬化症]](<del class="diffchange diffchange-inline">tuberous sclerosis complex,</del>[[TSC]])<del class="diffchange diffchange-inline">是一种常染色体显性遗传病,发病率为1/6000～1/10000.[[TSC]]患儿的临床表现具有年龄依赖性,新生儿期症状常不典型,临床上容易漏诊及误诊.</del></div></td><td class='diff-marker'>+</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins class="diffchange diffchange-inline">近几年FCD的发病机制已经被提出，磷脂酰肌醇3-激酶-蛋白激酶-雷帕霉素靶蛋白(PI3K-AKT-mTOR)信号通路的激活、GATOR对mTOR的作用、</ins>[[结节性硬化症]]([[TSC]])<ins class="diffchange diffchange-inline">基因突变、PTKs信号通路的基因突变、GABA受体假说、TRPC的激活、炎症等均可导致FCD，从而引发癫痫。</ins></div></td></tr> <tr><td class='diff-marker'>&#160;</td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'>&#160;</td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td></tr> <tr><td class='diff-marker'>−</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>===<del class="diffchange diffchange-inline">结节性硬化症患儿的临床、视频脑电图与影像学特征</del>===</div></td><td class='diff-marker'>+</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>===<ins class="diffchange diffchange-inline">一例结节性硬化症新生儿的TSC2基因变异分析</ins>===</div></td></tr> <tr><td class='diff-marker'>−</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del class="diffchange diffchange-inline">目的 分析</del>[[结节性硬化症]]([[TSC]])<del class="diffchange diffchange-inline">患儿的临床、视频脑电图(VEEG)和影像学特征.</del></div></td><td class='diff-marker'>+</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins class="diffchange diffchange-inline">分析一例</ins>[[结节性硬化症]](<ins class="diffchange diffchange-inline">tuberous sclerosis complex，</ins>[[TSC]])<ins class="diffchange diffchange-inline">新生儿的临床特点及遗传学特征。</ins></div></td></tr> <tr><td class='diff-marker'>&#160;</td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'>&#160;</td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td></tr> <tr><td class='diff-marker'>−</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>===<del class="diffchange diffchange-inline">结节性硬化症一家系4例报告</del>===</div></td><td class='diff-marker'>+</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>===<ins class="diffchange diffchange-inline">雷帕霉素治疗儿童结节性硬化症合并肾血管周上皮样细胞瘤2例</ins>===</div></td></tr> <tr><td class='diff-marker'>−</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>[[结节性硬化症]]([[TSC]])<del class="diffchange diffchange-inline">是一种常染色体显性遗传病,发病率为1</del>/<del class="diffchange diffchange-inline">600-</del>1/<del class="diffchange diffchange-inline">15400,以皮脂腺瘤,癫痫,智力低下为主要临床表现.</del></div></td><td class='diff-marker'>+</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>[[结节性硬化症]](<ins class="diffchange diffchange-inline">tuberous sclerosis complex，</ins>[[TSC]])<ins class="diffchange diffchange-inline">是一种常染色体显性遗传病，影响多个器官系统，发病率为1</ins>/<ins class="diffchange diffchange-inline">9000~</ins>1/<ins class="diffchange diffchange-inline">6000，其中1/3有家族史，2/3为散发病例。</ins></div></td></tr> <tr><td class='diff-marker'>&#160;</td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'>&#160;</td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td></tr> <tr><td class='diff-marker'>−</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>===<del class="diffchange diffchange-inline">结节性硬化的基因研究与诊断</del>===</div></td><td class='diff-marker'>+</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>===<ins class="diffchange diffchange-inline">一个结节性硬化症家系的临床表现及遗传学分析</ins>===</div></td></tr> <tr><td class='diff-marker'>−</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>[[结节性硬化症]]([[TSC]])<del class="diffchange diffchange-inline">是一种常染色体显性遗传疾病,由[[TSC]]1和[[TSC]]2两个基因异常引起,临床以智力低下、癫痫和面部血管纤维瘤三联症为主要表现,身体其他器官、组织也可受累.</del></div></td><td class='diff-marker'>+</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins class="diffchange diffchange-inline">明确1例临床诊断为</ins>[[结节性硬化症]](<ins class="diffchange diffchange-inline">tuberous sclerosis complex，</ins>[[TSC]])<ins class="diffchange diffchange-inline">患者的致病基因，为临床诊断及遗传咨询提供依据。</ins></div></td></tr> <tr><td class='diff-marker'>&#160;</td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td><td class='diff-marker'>&#160;</td><td style="background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;"></td></tr> <tr><td class='diff-marker'>−</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>===<del class="diffchange diffchange-inline">CT和MRI在结节性硬化症中的诊断价值</del>===</div></td><td class='diff-marker'>+</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>===<ins class="diffchange diffchange-inline">结节性硬化症患者基因突变与临床表型的关系</ins>===</div></td></tr> <tr><td class='diff-marker'>−</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del class="diffchange diffchange-inline">目的 研究CT及MRI在</del>[[结节性硬化症]](<del class="diffchange diffchange-inline">Tuberous Sclerosis Complex简写</del>[[TSC]])<del class="diffchange diffchange-inline">中的诊断价值.</del></div></td><td class='diff-marker'>+</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>[[结节性硬化症]](<ins class="diffchange diffchange-inline">tuberoussclerosiscomplex，</ins>[[TSC]])<ins class="diffchange diffchange-inline">是一种常染色体显性遗传、以多器官错构瘤为特征的疾病，特别是在脑部、肾脏、心脏和皮肤。</ins></div></td></tr> </table>

Admin http://120.24.161.253:5617/index.php?title=%E7%BB%93%E8%8A%82%E6%80%A7%E7%A1%AC%E5%8C%96%E7%97%87-%E5%90%8C%E4%B9%89%E8%AF%8D-TSC&diff=2007129&oldid=prev 2026-04-13T13:56:59Z

<p>修改1</p> <p><b>新页面</b></p><div>主实体：[[结节性硬化症]]，关系：[[同义词]] ，尾实体：[[TSC]]<br /> <br /> ==关系介绍==<br /> 待补充<br /> <br /> ==来源==<br /> ===结节性硬化症临床研究进展===<br /> 目前研究发现[[结节性硬化症]]基因1、2([[TSC]]1、[[TSC]]2)是其致病基因,该文就[[TSC]]发病机制及最新研究综述如下.<br /> <br /> ===新生儿结节性硬化症===<br /> [[结节性硬化症]](tuberous sclerosis complex,[[TSC]])是一种常染色体显性遗传病,发病率为1/6000～1/10000.[[TSC]]患儿的临床表现具有年龄依赖性,新生儿期症状常不典型,临床上容易漏诊及误诊.<br /> <br /> ===结节性硬化症患儿的临床、视频脑电图与影像学特征===<br /> 目的 分析[[结节性硬化症]]([[TSC]])患儿的临床、视频脑电图(VEEG)和影像学特征.<br /> <br /> ===结节性硬化症一家系4例报告===<br /> [[结节性硬化症]]([[TSC]])是一种常染色体显性遗传病,发病率为1/600-1/15400,以皮脂腺瘤,癫痫,智力低下为主要临床表现.<br /> <br /> ===结节性硬化的基因研究与诊断===<br /> [[结节性硬化症]]([[TSC]])是一种常染色体显性遗传疾病,由[[TSC]]1和[[TSC]]2两个基因异常引起,临床以智力低下、癫痫和面部血管纤维瘤三联症为主要表现,身体其他器官、组织也可受累.<br /> <br /> ===CT和MRI在结节性硬化症中的诊断价值===<br /> 目的 研究CT及MRI在[[结节性硬化症]](Tuberous Sclerosis Complex简写[[TSC]])中的诊断价值.</div>

Admin